ea0077lb31 | Late Breaking | SFEBES2021
Stasinopoulos Ioannis
, Khan Shazia
, MacKay Logan
, Brown Roger
, Bailey Matthew
, Andrew Ruth
Aldosterone and glucocorticoids stimulate sodium transport by the renal tubule, which is important for blood pressure homeostasis. Corticosteroid excess and/or abnormal steroid hormone activity within the kidney can cause hypertension. Circulatory and urinary steroid concentrations can be measured routinely but steroid concentrations at a tissue and cellular level are largely unknown, and the kidney remains a black box. Mass spectrometry imaging (MSI) permits local...